Electron microscopic study of ring-shaped, bivalent hapten, bivalent antidansyl monoclonal antibody complexes with identical variable domains but IgG1, IgG2a and …

ML Phillips, VT Oi, VN Schumaker - Molecular immunology, 1990 - Elsevier
hapten, bis-dansyl cadaverine. We believe these are the first electron microscope studies of
bivalent hapten, antibody rings formed with monoclonal antibodies and from a species other …

Human/mouse chimeric monoclonal antibodies with human IgG1, IgG2, IgG3 and IgG4 constant domains: electron microscopic and hydrodynamic characterization

ML Phillips, T Mi-Hua, SL Morrison… - Molecular immunology, 1994 - Elsevier
… with the same murine anti-dansyl variable domain but constant … of two antibodies forming a
ring-shaped complex, presumably … fields of complexes of bivalent hapten with IgGl, IgG2 and …

Immunoglobulin structure and function as revealed by electron microscopy

KH Roux - International archives of allergy and immunology, 1999 - karger.com
IgG and molecules crosslinked by bivalent haptens were … For the murine IgG1, IgG2a, and
IgG2b subclasses, most of … by our analysis to be about as able to wag its Fab arms as IgG2. …

Flexibility of human IgG subclasses.

KH Roux, L Strelets, TE Michaelsen - Journal of immunology …, 1997 - journals.aai.org
IgG subclass Ab molecules (IgG1, IgG2, IgG3, and IgG4) that share … study, the lgGs were
reacted with a short divalent hapten (bis-… to our anti-Ids, the affinity of the antidansyl system is …

Comparisons of the ability of human IgG3 hinge mutants, IgM, IgE, and IgA2, to form small immune complexes: a role for flexibility and geometry

KH Roux, L Strelets, OH Brekke, I Sandlie… - the Journal of …, 1998 - journals.aai.org
… Investigations by others using divalent haptens show that ring dimers of … bivalent antidansyl
mAb complexes with identical variable domains but IgG1, IgG2a and IgG2b constant domains

Variable region domain exchange influences the functional properties of IgG

SL Morrison, SB Porter, KR Trinh, LA Wims… - The Journal of …, 1998 - journals.aai.org
… present study we have characterized a family of anti-dansyl … The geometric presentation
of hapten or antigenic epitopes … with identical variable domains but IgG1, IgG2a and IgG2b

Monitoring the formation of soluble immune complexes composed of idiotype and anti-idiotype antibodies by electron microscopy

KH Roux, NS Greenspan - Molecular immunology, 1994 - Elsevier
… VN (1990) Electron microscopic study of ring-shaped, bivalent hapten, bivalent antidansyl
monoclonal antibody complexes with identical variable domains but IgGl, IgG2a and IgG2b

[HTML][HTML] Solution conformation of wild-type and mutant IgG3 and IgG4 immunoglobulins using crystallohydrodynamics: possible implications for complement activation

Y Lu, SE Harding, TE Michaelsen, E Longman… - Biophysical journal, 2007 - cell.com
complexes: a systematic study using chimeric anti-NIP … IgG1 and IgG3 can active-complement
effectively, IgG2 only … end of the first heavy-chain constant region domain (C H 1) and the …

Dynamical structure of the hinge region of immunoglobulin G as studied by 13C nuclear magnetic resonance spectroscopy

HH Kim, C Matsunaga, A Yoshino, K Kato… - Journal of molecular …, 1994 - Elsevier
… are still mobile in a hapten-linked dimeric complex of lgG2a (… heavy Chain of IgG2’a(s)RA
is readily cleaved within several … rabbit antidansyl monoclonal antibodies with the V" and VL …

AN ELECTRON MICROSCOPIC VIEW OF THE GEOMETRY AND DYNAMICS OF IDIOTYPE-ANTI-IDIOTYPE

Y Shoenfeld, RC Kennedy… - Idiotypes in Medicine …, 1997 - books.google.com
Electron microscopic study of ring-shaped, bivalent hapten, bivalent antidansyl
monoclonal antibody complexes with identical variable domains but IgG1, IgG2a and IgG2b